Fth1 uniprot
WebNov 3, 2014 · The iron storage protein ferritin is a complex of 24 ferritin light chain (FTL; 134790) and ferritin heavy chain (FTH1) subunits in ratios that vary in different cell types. FTH subunits exhibit ferroxidase activity, converting Fe (2+) to Fe (3+), so that iron may be stored in the ferritin mineral core, which prevents undesirable reactions of ... WebBackground. Ferritin (FTH) is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and bioavailable form (1). The assembled ferritin …
Fth1 uniprot
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WebFTH1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. WebUniProt accession no. P02794. shipped in. dry ice. storage temp. −20°C. Gene Information. human ... FTH1(2495) Related Categories. ... FTH1 can also be used as a possible prognostic marker for breast cancer. Physical form. Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. ...
WebFTH1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. All transcripts of all genes have been analyzed ...
Web14319 Ensembl ENSG00000167996 ENSMUSG00000024661 UniProt P02794 P09528 RefSeq (mRNA) NM_002032 NM_010239 RefSeq (protein) NP_002024 NP_034369 Location (UCSC) Chr 11: 61.96 – 61.97 Mb Chr 19: 9.96 – 9.96 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Ferritin heavy chain is a ferroxidase enzyme … This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multipl…
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. See more
WebMar 21, 2024 · GeneCards Summary for FTH1 Gene. FTH1 (Ferritin Heavy Chain 1) is a Protein Coding gene. Diseases associated with FTH1 include Hemochromatosis, Type 5 … jon braidley marathonWebJun 9, 2024 · In our study, we observed increased ferritin (Fth1) levels in both 4 dpi and 14 dpi lung tissues sample which corroborates with the recent findings where its increased expression has been reported in COVID‐19 patients. 52, 53 Further studies are warranted to evaluate its role as a pathogenic mediator in COVID‐19. In addition, we also report ... how to install bilco doorWebferritin heavy chain Antibody (B-12) is an IgG2a κ mouse monoclonal FTH1 antibody that is recommended for WB, IP, IF and ELISA. 58 citations. Choose a Store Santa cruz biotechnology. Santa Cruz Animal Health ... UniProt ID: P02794: 134770: Mouse: Fth1: Entrez Gene ID: 14319: 19 A: NM_010239: jon bray facebookWeb丁香通为您提供or2t3or2t34o商品详情介绍：价格：￥1320，货号：csb-pa009463，品牌：cusabio，产地：cn，详见丁香通or2t3or2t34o商品详情页； jon braun facebookWebThen, each target of active ingredients, depression and ferroptosis were searched in the UniProt database 45 to get the UniProt gene ID. Here, 12,608 depression-related targets and 260 ferroptosis-related targets were screened out. ... Inhibition of NRF2 or FTH1 can significantly promote the content of Fe 2+ and the occurrence of ferroptosis, ... how to install bilco cellar doorsWebFTH1, FTL. UniProt ID (Human) P02794, (Human) P02792. Show Less . About This Kit. The Human Ferritin ELISA quantitates Hu Ferritin in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu Ferritin. Principle of the method jon bray twitterWebMonoclonal Anti-FTH1 antibody produced in mouse ~1.0 mg/mL, clone FTH24, purified immunoglobulin. View Price and Availability. Sigma-Aldrich. SAB1410457. ... UniProt accession no. P02794. shipped in. dry ice. storage temp. −20°C. Gene Information. human ... FTH1(2495) Description. Immunogen. jon bragman inc