WebSep 8, 2024 · The molecular pathway identified is controlled by an evolutionary conserved gene called a Grainyhead like 3 (GRHL3), which is a gene required for mammalian development. Without this gene, several abnormalities may occur, including spina bifida, defective epidermal barrier, defective eyelid closure and soft-tissue syndactyly, a … WebThe transcription factor Grainyhead-like 3 (GRHL3) plays an important role in the development and differentiation of normal urothelium. The contribution to UCB …
Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer
WebSep 4, 2024 · Mouse models have demonstrated a crucial role for members of the grainyhead-like family of transcription factors in neural tube closure. Grhl3 -null … WebSep 17, 2015 · In addition, the planar cell polarity protein Grainyhead-like-3 (Grhl3) and E-cadherin have been previously shown to regulate EPB acquisition by mediating SC formation, cell adhesion and/or extracellular lipid composition in the SG in vivo [19–22]. Taken together, these data indicate that an intact polarity network is necessary for EPB ... dauphin county dispatch log
Overexpression of Grainyhead-like 3 causes spina bifida …
WebOct 19, 2024 · The transcription factor Grainyhead-like 3 (GRHL3) is essential for maintaining barrier integrity and preventing development of cutaneous squamous cell carcinoma (SCC); however, how loss of this ... WebMar 11, 2024 · We previously demonstrated that the transcription factor Grainyhead-like 3 (GRHL3) has essential functions in endothelial cells by inhibiting apoptosis and promoting migration as well as activation of … WebAug 5, 2024 · XM_011510343.3 → XP_011508645.1 grainyhead-like protein 1 homolog isoform X2. Conserved Domains (1) summary pfam04516 Location: 188 → 395 CP2; CP2 transcription factor; XM_047444018.1 → XP_047299974.1 grainyhead-like protein 1 homolog isoform X5. XM_017003900.2 → XP_016859389.1 grainyhead-like protein 1 … dauphin county detention center