Web2 mei 2024 · fibrosis with a mild or severe phenotype in mice expressing transforming growth factor-beta1 (TGF-β1) under the control of a mouse albumin promoter (Alb/TGF-β1), on a mixed genetic background with CBAxC57Bl6 mice. Here, we aimed to examine how genetic background may influence kidney fibrosis in TGF-β1 transgenic mice, and in … Web4 mrt. 2024 · Salidroside (Sal) is an active ingredient that is isolated from Rhodiola rosea, which has been reported to have anti-inflammatory activities and a renal protective effect. However, the role of Sal on renal fibrosis has not yet been elucidated. Here, the purpose of the current study is to test the protective effects of Sal against renal interstitial fibrosis …
Commonly used stains for the histologic assessment of renal fibrosis ...
WebInterstitial fibrosis is a hallmark structural correlate of progressive and chronic kidney disease. There remain many uncertainties about how to best measure interstitial fibrosis both in... Web11 apr. 2024 · Methods: We included urine samples from 46 adults and pediatric biopsy-proven lupus nephritis patients who underwent clinically indicated kidney biopsies … fma lizenzen
Renal histology in diabetic nephropathy predicts progression to …
Web2 mrt. 2010 · Recently, early biomarkers of renal interstitial fibrosis have been identified, amongst them de novo expression of vimentin by tubular epithelial cells, which is an intermediate filament, and the translocation of beta-catenin into their cytoplasm. Web21 aug. 2024 · Background Interstitial fibrosis and tubular atrophy (IFTA) is a strong predictor of decline in kidney function. Non-invasive test to assess IFTA is not available. Methods We trained, validated and tested a deep learning (DL) system to classify IFTA grade from 6,135 ultrasound images obtained from 352 patients who underwent kidney … Web17 mrt. 2024 · Activating SIRT1 by resveratrol reduces interstitial fibrosis via suppressing acetylated Smad3 and MMP-7 in UUO mice. 202,203 Honokiol alleviated the acetylation level and kidney fibrosis, whose ... f.m. allen elephant hat