Poly rc -binding protein 1
WebMay 21, 2024 · Poly rC binding protein 1 (PCBP1) is a multifunctional protein that serves as a cytosolic iron chaperone, binding and transferring iron to recipient proteins in … WebNov 14, 2024 · Poly(rC)-binding proteins (PCBPs), a defined subfamily of RNA binding proteins, are characterized by their high affinity and sequence-specific interaction with …
Poly rc -binding protein 1
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WebSep 11, 2003 · Here, we show that members of the poly (rC) binding protein family, poly (rC) binding protein 1 (PCBP1), poly (rC) binding protein 2 (PCBP2) and hnRNPK were able to activate the IRES in vitro up ... WebThe hepatitis C virus (HCV) co-opts numerous cellular elements, including proteins, lipids, and microRNAs, to complete its viral life cycle. The cellular RNA-binding protein, poly(rC)-binding protein 1 (PCBP1), was previously reported to bind to the 5′ untranslated region (UTR) of the HCV genome; however, its importance in the viral life cycle has remained …
WebMay 21, 2024 · Poly rC binding protein 1 (PCBP1) is a multifunctional protein that serves as a cytosolic iron chaperone, binding and transferring iron to recipient proteins in mammalian cells. Although PCBP1 distributes iron in cells, its role in managing iron in mammalian tissues remains open for study. WebMay 11, 2024 · Poly(rC)-binding protein1 (PCBP1) is an RNA-binding protein that regulates mRNA stability, splicing, and translation. PCBP1 is a tumor suppressor and can inhibit the translation of several oncogenic genes. ... Poly(rC) binding protein 1 represses the translation of STAT3 through 5' UTR. @article{Li2024PolyrCBP, title={Poly ...
WebMay 1, 2024 · Poly(rC)-binding protein 1 (PCBP1) is a multifunctional RNA-binding protein that plays various roles in gene transcription, RNA regulation, and iron chaperone [8, 9]. PCBP1 is a major iron chaperon facilitating iron loading to ferritins and an RNA-binding protein interacting with other target protein BolA2 independently at its different faces [10]. WebMay 10, 2024 · Objective To monitor the phosphorylation modifications and cellular localization of poly(rC)-binding protein-1 (PCBP1) during the cell cycle progression of Hela cells. Result Hela cells highly synchronized at five different phases from interphase to mitosis were obtained. Using mitotic phosphoprotein-specific monoclonal antibody MPM …
WebJun 14, 2024 · Poly(rC)-binding protein 1 (PCBP1) is a multifunctional protein that coordinates both RNA and iron. PCBP1 was initially identified as a component of …
WebCommon to processing body (P body) and stress granule. K12889 PCBP1; poly (rC)-binding protein 1. Spliceosome [BR: ko03041] Common components. Common spliceosomal components. hnRNP proteins. K12889 PCBP1; poly (rC)-binding protein 1. BRITE hierarchy. crypto tax software defiWebDec 8, 2024 · Poly(rC) Binding Protein 1 Represses the Translation of STAT3 through 5' UTR. Li Z, Wang X, Jia RLi Z, et al. Curr Gene Ther, 2024. PMID 35549870; Poly(rC)-Binding … crypto tax software south africaWebJan 20, 2024 · We found a C-rich element (CRE) in mu-opioid receptor (MOR) 3'-untranslated region (UTR) to which poly (rC) binding protein 1 (PCBP1) binds, resulting in MOR mRNA … crypto tax software that works with turbotaxWebAug 21, 2024 · However, splicing factors can also play negative roles in tumorigenesis. In the current review, we focus on splicing factor poly(rC)-binding protein 1 (PCBP1), a novel tumor suppressor that is characterized by downregulation in many cancer types and shows inhibition of tumor formation and metastasis. crypto tax softwaresWebSep 1, 2015 · PCBP1 is an intron‐less gene encoding the 356 amino acid poly(rC) binding protein 1, which contains three K‐Homology (KH) domains and two nuclear localization signals. The mutations predominantly (10/12, 83%) affect the KH III domain, either by complete domain loss or amino acid changes. crypto tax specialist near meWebJan 29, 2024 · The hepatitis C virus (HCV) co-opts numerous cellular elements, including proteins, lipids, and microRNAs, to complete its viral life cycle. The cellular RNA-binding … crypto tax spainWebA protein covalently linked to poliovirus genome RNA. Proc Natl Acad Sci U S A. 1977 Jan; 74 (1):59–63. [PMC free article] [Google Scholar] Leffers H, Dejgaard K, Celis JE. Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains. Eur J Biochem. 1995 Jun 1; 230 (2):447–453. crypto tax solutions